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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC18A3
All Species:
17.88
Human Site:
Y352
Identified Species:
35.76
UniProt:
Q16572
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q16572
NP_003046.2
532
56961
Y352
T
V
R
L
A
A
R
Y
P
H
L
Q
W
L
Y
Chimpanzee
Pan troglodytes
XP_001138996
532
56986
Y352
T
V
R
L
A
A
R
Y
P
H
L
Q
W
L
Y
Rhesus Macaque
Macaca mulatta
XP_001107292
532
57072
Y352
T
V
R
L
A
A
R
Y
P
H
L
Q
W
L
Y
Dog
Lupus familis
XP_543901
528
56326
Y348
T
V
R
L
A
A
R
Y
P
H
L
Q
W
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
O35304
530
56597
A350
Y
L
T
V
R
L
A
A
R
Y
P
H
L
Q
W
Rat
Rattus norvegicus
Q62666
530
56519
A350
Y
L
T
V
R
L
A
A
R
Y
P
H
L
Q
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_996865
522
55424
Y333
T
V
R
L
A
A
A
Y
P
H
L
Q
W
L
Y
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
P59845
493
53034
R314
L
A
A
R
Y
P
E
R
Q
W
F
Y
G
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O17444
578
64295
D384
P
T
L
G
Y
L
V
D
V
R
Y
V
S
V
Y
Honey Bee
Apis mellifera
XP_624140
581
64261
L367
A
L
I
D
T
A
L
L
P
T
L
G
Y
L
V
Nematode Worm
Caenorhab. elegans
P34711
532
58625
F331
T
V
K
M
L
R
A
F
P
H
H
T
W
A
I
Sea Urchin
Strong. purpuratus
XP_782213
561
61607
A331
T
V
K
L
A
S
R
A
P
H
Y
Q
W
L
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
98.3
87.7
N.A.
93.8
94.1
N.A.
N.A.
66.5
N.A.
66.7
N.A.
46.7
49
45.2
51.1
Protein Similarity:
100
99.2
99
90
N.A.
94.5
94.9
N.A.
N.A.
78
N.A.
76.5
N.A.
61.5
62.8
59.7
67.2
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
N.A.
93.3
N.A.
0
N.A.
6.6
26.6
33.3
66.6
P-Site Similarity:
100
100
100
100
N.A.
26.6
26.6
N.A.
N.A.
93.3
N.A.
0
N.A.
13.3
40
53.3
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
9
0
50
50
34
25
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
9
0
0
9
0
0
0
0
% F
% Gly:
0
0
0
9
0
0
0
0
0
0
0
9
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
59
9
17
0
0
0
% H
% Ile:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% I
% Lys:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
9
25
9
50
9
25
9
9
0
0
50
0
17
59
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
9
0
0
0
0
9
0
0
67
0
17
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
50
0
17
0
% Q
% Arg:
0
0
42
9
17
9
42
9
17
9
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
9
0
0
0
0
0
0
9
0
0
% S
% Thr:
59
9
17
0
9
0
0
0
0
9
0
9
0
0
0
% T
% Val:
0
59
0
17
0
0
9
0
9
0
0
9
0
9
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
59
0
17
% W
% Tyr:
17
0
0
0
17
0
0
42
0
17
17
9
9
0
50
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _